This photograph collection contains images of hospital physicians, nurses, staff, patients, as well as the buildings and grounds of the institution, including Grady Memorial Hospital, the Grady Memorial School of Nursing, and Hughes Spalding Pavilion. Among the images are photographs taken during special events, such as retirement ceremonies, graduations, Christmas parties, and receptions.

This collection contains a single scrapbook documenting the seventy-fifth birthday of Hughes Spalding. The scrapbook includes photographs, a menu, guest list, and biography.